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Abnormal Uterine Bleeding

Abnormal Uterine Bleeding

Includes Heavy Menstrual Bleeding ( Mennorhagia ), Irregular,  Intermenstrual and Post Coital Bleeding

Normal Menstrual Cycle

A “normal” menstrual cycle is defined based on 4 parameters (frequency, regularity, duration, or volume) summarised in the table below

​Parameter Normal Limits​(5th to 95th centile)
Frequency of menses (days)24 to 38 days
Regularity (Cycle length)≤7 to 9 days
Duration (days of bleeding in a single menstrual period)≤8 days
​Volume (monthly blood loss)Clinical definition is subjective and
defined as a volume of menstrual blood loss that does not interfere with a woman’s physical, social, emotional, and/or quality of life

Abnormal Uterine Bleeding

is the overarching term used to describe any symptomatic variation from normal menstruation and also includes intermenstrual bleeding. The Table below  summarises the recommended terminology for women with AUB.

Parameters Terminology Out with 5th to 95th centile
Frequency of menses (days)Absent Amenorrhoea – Primary or Secondary
 Infrequent >38 days
 Frequent <24 days
Regularity (Cycle length)IrregularVariation >10 days  – Cycle length is the number of days from the first day of one menstrual cycle to the first day of the next
Duration (days of bleeding in a single menstrual period)Prolonged> 8 days
Volume (monthly blood loss)Heavy or lightSubjectively defined
Spontaneous bleeds occurring in between periods Intermenstrual
bleeding
(IMB)
Cyclic (early, mid, late cycle) or random, Midcycle IMB may represent a nadir in estradiol levels (ovulation) and is physiological (9% of women).

Causes – See Fig Below PALM- COEIN System to identify potential Causes of AUB

Diagram reproduced from “Biomarkers in abnormal uterine bleeding -Rohan Chodankar, Hilary O D Critchley Biology of Reproduction/ ioy231, https://doi.org/10.1093/biolre/ioy231

See Risk assessment for STI and Chlamydia referral guidance on the STI RefHelp page

Monthly menses chartMenstrual blood loss chart