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Malignant Pleural Effusion

Information                                                                                                                             

A malignant pleural effusion is a build up of fluid containing cancer cells between the membranes that line the lungs. This condition is a sign that the cancer has spread, or metastasized, to other areas of the body. Common cancers that cause malignant effusions include lymphoma and cancers of the breast, lung, and ovary. A malignant pleural effusion is treatable. But it can be a serious and potentially life-threatening condition.

Most common symptoms are shortness of breath, dry cough, pain, feeling of chest heaviness or tightness, inability to lie flat.                                                                                                                   

All invasive pleural interventions should be performed under the auspices of appropriately trained clinicians in the respiratory department. 

Who to refer:

All patients with a cancer diagnosis with symptoms suggestive of a malignant pleural effusion should be discussed with pleural service.

Who not to refer:

If in doubt please do not hesitate to call Acute Oncology teamat the Edinburgh Cancer Centre on 07798774842 or 0131 537 1000 and ask to speak to Acute Oncology teamfor oncology.

How to refer:

The contact email for the pleural service (non urgent referrals) is: PleuralService.WGH@nhslothian.scot.nhs.uk or alternatively if more urgent advice is needed contact the respiratory team on call via 0131 537 1000.

All patients on or within 6 weeks of treatment should be encouraged to monitor symptoms and call Cancer Treatment Helpline (CTH) on 08009177711 if any treatment related concerns. Please note the CTH is a call operator service provided by NHS 24 who then refer on to acute care specialist. They are not able to give specialist advice.  Note if a patient has presented to primary care for assessment the patient should not be advised to call the CTH to pass on this information or seek further advice. The primary care clinician should call the Acute Oncology team at the Edinburgh Cancer Centre to discuss if appropriate. 

Link to Acute Oncology Initial Management Guidelines:

UKONS | Acute Oncology Initial Management Guidelines (sundownsolutions.co.uk)