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Paget’s Disease of Bone

Pagets Disease of Bone

History

Patients may present with a variety of symptoms including:

  • Bone pain  
  • Bone deformity
  • Pathological fracture
  • Deafness
  • Osteoarthritis
  • Incidental finding as the result of imaging or a blood test performed for another reason

Examination

  • Most patients have no abnormalities detectable on clinical examination
  • Where there is bone deformity, this usually affects the tibia, skull or femur

Investigations

  • Routine biochemistry (raised ALP, with otherwise normal LFT, calcium and U&E)
  • X-ray pelvis and lumbar spine (abnormal in 70% of patients)

M.A & S.R – 28-9-26

When to refer

Patients suspected to have Paget’s should be referred for evaluation to determine if specific treatment is indicated.

Initial management

If symptoms such as pain are present, treat on a symptomatic basis pending clinic review.