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Raised PSA

https://www.cancerreferral.scot.nhs.uk/urological-cancers/?alttemplate=Guideline

R.M & H.S 13-05-20

Who to refer

Men with raised PSA according to the following age-adjusted limits:

  • Age 59 years or less: PSA greater than or equal to 3.0μg/l
  • Age 60 to 69 years: PSA greater than or equal to 4.0μg/l
  • Age 70 or over: PSA greater than or equal to 5.0μg/l

Before having a PSA test men should NOT have:

  • an active urinary infection (PSA may remain raised for many months)
  • ejaculated in the previous 48 hours
  • exercised vigorously in the previous 48 hours
  • had a prostate biopsy in the previous 6 weeks
  • had a DRE within the previous week
  • Prostate Cancer Risk Management Programme – PSA Testing [Adobe Acrobat PDF – 670KB]

Who not to refer

  • Men who have a raised PSA as a result of urinary tract infection or recent urinary tract instrumentation or catheterisation.
  • Where the PSA is raised in these situations, it should be repeated six weeks later. 
  • Referral is indicated if it remains elevated.
  • If there is a downward trend, it can be monitored until it returns to normal.
  • Men with significant co-morbidities, especially those aged 70 or over, should not undergo prostate biopsy without careful consideration of whether a diagnosis of prostate cancer is in their interests.
  • Please indicate any such co-morbidities on the referral and we will arrange for clinic consultation before biopsy is indicated.
  • PSA testing in elderly men is not recommended unless a diagnosis of prostate cancer is relevant to that particular patient’s situation, and will affect their management.

How to refer

  • Via SCI Gateway.