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Barrett’s Oesophagus

Barretts Oesophagus

Requires Endoscopic Surveillance:

​If patient has less than 1cm of Barrett’s oesophagus then no biopsies and no follow up required.​

For those with Histologically proven Barrett’s oesophagus greater than or equal to 1cm length, follow up interval depends on presence of dyplasia and length of Barrett’s segment*

* follow-up by cytosponge with endoscopy for selected cases.

Do not routinely offer OGD to those with GORD to diagnose Barrett’s especially if <age 50

Consider referral if long standing GORD especially if

  • Age 50 years or older
  • long duration of symptoms
  • worsening symptoms
  • male
  • previous hiatus hernia or oesophagitis
  • obesity (BMI>30)
  • family history of Barrett’s or oesophageal adenocarcinoma

Barrett’s oesophagus Treatment

  • Offer long term maintenance full dose PPI (eg omeprazole 20mg daily)
  • Remain on full dose PPI (high dose may be necessary to control symptoms)
    • High dose PPI (eg omeprazole 40mg daily)
  • Switch to another PPI at full or high dose if initial PPI fails to control symptoms

 Follow up of Barrett’s oesophagus (NHS Lothian)*

  • If patient has less than 1cm of Barrett’s oesophagus then no biopsies and no follow up required
  • After diagnosis, endoscopic follow up interval depends on
  •  presence of dysplasia and
  • length of Barrett’s segment
  • If dysplasia is absent OGD, next follow-up should be repeated in 1 year
  • If dysplasia is absent at 1year, subsequent follow up interval depends on length of Barrett’s segment.

Barrett’s >3cm

  • OGD every 3 years*

All others

  • OGD every 5 years

*Follow-up currently by cytosponge with endoscopy for selected cases

If there is doubt about presence of dysplasia OGD is repeated after 6 months (usually with increased PPI dose)

If Low grade dysplasia (LGD) is present OGD is repeated every 6 months until either

If high grade dysplasia (HGD) is present – urgent referral to GI services at RIE