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Ankylosing Spondylitis

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NHSLIntegratedBackPainPathway.aspx

Sites of pain in AS

History

  • Low back pain and stiffness in sacroiliac region sometimes radiating to buttocks
  • Marked early morning stiffness improving as the day goes on
  • Onset late teens or early 20’s.
  • May be associated with iritis and inflammatory bowel disease

Examination

  • Reduced range of spine movements
  • Chest expansion reduced

Investigations

  • ESR and CRP (often raised but may be normal)
  • X-rays of pelvis and lumbar spine (sacroileitis and possibly syndesmophytes but may be normal in early disease)

​Referral

Patients with a characteristic history should be referred to the rheumatology service, even if bloods and x-rays are normal.

Main differential diagnoses

Prolapse intervertebral disc – Pain follows nerve root distribution.

Mechanical back pain – Worse on movement, relieved by rest

​Initial management

Treat symptoms with full dose NSAID / and or analgesics pending clinic review.

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