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Drugs associated with Abnormal LFTs

Drugs associated with Abnormal LFTs

This list is not exhaustive and there may be a mixed pattern of abnormal LFTs. Please see the BNF for further information.

Cholestatic pattern (ALP/GGT)

Cytotoxic pattern ( ALT)

Co-amoxiclav

Allopurinol

Anabolic steroids

Amiodarone

Chlorambucil

Aspirin

Chlorpromazine

zathioprine/6-Mercaptopurine

Chlorpropamide

Carbamazepine

Clopridogrel

Etretinate

Colchicine

HAART drugs

Erythromycin

Hydralazine

Estrogen (oral contraceptives)

Isoniazid

Flucloxacillin

NSAIDs

Mirtazapine

Ketoconazole/Fluconazole

Phenobarbital

Lisinopril

Terbinafine

Methotrexate

6-Mercaptopurine

Methyldopa

Nitrofurantoin

Nicotinic acid (especiallyS/R)

Omeprazole

Paracetamol

Paroxetine

Phenytoin

Propylthiouracil

Rifampin

Risperidone

“Statins”

Sertraline

Sulfonamides

Tetracyclines

Tricyclics

Trimethoprim

Trazodone

Valproate

(Taken from: http://www.medicinenet.com/liver_blood_tests/page4.htm#6whatmedications)