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Rheumatoid Arthritis

History

  • Joint pain stiffness and swelling in a symmetrical distribution affecting the wrists, MCP and PIP joints of the hands and MTP joints of the feet. Large joints may also be affected.
  • Early morning stiffness (typically >30min)
  • Inactivity gelling (stiffness after a period of inactivity)

Examination

  • Soft tissue swelling and tenderness of affected joints
  • Pain on squeezing MCP and MTP joints (the squeeze test).

Investigations

  • FBC, ESR, LFT,
  • Anti-CCP antibodies
  • X-ray of the hands (periarticular osteoporosis, erosions)
JOINT DISTRIBUTION (0-5)
1 large joint0
2-10 large joints1
1-3 small joints (large joints not counted)2
4-10 small joints (large joints not counted)3
>10 joints (at least one small joint)5
SEROLOGY (0-3)
Negative RF AND negative ACPA0
Low positive RF OR low positive ACPA2
High positive RF OR high positive ACPA3
SYMPTOM DURATION (0-1)
<6 weeks0
≥6 weeks1
ACUTE PHASE REACTANTS (0-1)
Normal CRP AND normal ESR0
Abnormal CRP OR abnormal ESR1

M.A & S.R/H.B. 25-01-24

When to refer:

Patients with swollen joints, significant morning stiffness. Refer for urgent appointment if scoring( above) is high.

How to refer:

SCI Gateway > Rheumatology > WGH

Main differential diagnoses

Viral arthritis – Can present similarly but usually resolves within 4-6 weeks

Osteoarthritis – The distribution is different (affects DIP, PIP and 1st CMC joints of the hands). There is bony joint swelling due to osteophytes. Levels of ESR and CRP are normal and CCP is negative.

Psoriatic arthritis – the distribution is different and CCP is negative.

Initial management

Treat symptoms with NSAID / and or analgesics pending clinic review.

Please avoid giving corticosteroids.

If patient is very symptomatic or has systemic features please discuss with on-call team for an early appointment.

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