For patients on HRT, please see Unscheduled Bleeding on HRT

MM & RC 22/1/26
Who to refer:
Patients with Post-Menopausal Vaginal Bleeding and:
- Clinical examination suggests vulval/vaginal/cervical malignancy
- Currently using Tamoxifen or have used it in the past
- Lynch or Cowden Syndrome
- BRCA1 or BRCA2 carriers without bilateral salpingo-oophrectomy
- Pelvic USS with endometrial thickness (≥5.0mm): we now ask all clinicians to send an onward referral to Gynaecology (RIE>Gynaecology>PMB abnormal scan result)
- Pelvic USS where a copper IUCD present or Progesterone IUCD present for >5 years
- Pelvic USS with ovarian pathology (see ovarian cyst and ovarian cancer pathway)
- Second or subsequent episode(s) of PMB, more than 6 months since reassuring prior assessment (even if endometrium <5.0mm on prior Pelvic USS)B.
For patients on HRT, please see Unscheduled Bleeding on HRT.
There are 2 situations, as below, where patients who are, or have recently been, on HRT should be referred for a PMB USS (not an Unscheduled Bleeding on HRT USS):
- Ongoing unscheduled bleeding after a total of 12 months of HRT despite troubleshooting actions (Unscheduled Bleeding on HRT)
- Ongoing bleeding at 6 weeks since stopping HRT (Unscheduled Bleeding on HRT)
Who not to refer:
- Women with PMB, normal clinical examination and endometrial thickness less than 5.0mm, in the absence of focal pathology e.g. polyp.
How to refer:
1. For patients with PMB
Refer to Radiology for PMB USS Sci-Gateway > ELCH/LB/RIE/SJH > Clinical Radiology > LI PMB (No HRT)
If the USS report is reported as abnormal (ET ≥5mm) Primary Care Clinician to refer patient to Gynaecology
Sci-Gateway > RIE > Gynaecology > LI PMB Abnormal Ultrasound
Where the USS is reported as abnormal (ET ≥5mm) the report will be emailed by radiology to the Clinical Inbox of the referring GP practice and will require the Primary Care Clinician to inform the patient and to send a USOC SCI Gateway referral. It will also be emailed to the Gynaecology cancer clinic.
2. For patients with PMB on tamoxifen
USOC Referral Gynaecology Sci-gateway > RIE > Gynaecology > LI Basic sign referral (select priority USOC) and simultaneous referral to Radiology for PMB USS Sci-Gateway > ELCH/LB/RIE/SJH > Clinical Radiology > LI PMB (No HRT)
3.For suspected vulval, vaginal, cervical malignancy:
USOC Referral Gynaecology Sci-Gateway > RIE> Gynaecology> LI Basic sign referral (select priority USOC)
4.For recurrent/persistent PMB:
USOC Referral Gynaecology Sci-gateway > RIE > Gynaecology > LI Basic sign referral (select priority USOC) and simultaneous referral to Radiology for PMB USS Sci-Gateway > ELCH/LB/RIE/SJH > Clinical Radiology > LI PMB (No HRT)
5.For patients with ongoing unscheduled bleeding after a total of 12 months of HRT despite troubleshooting actions Unscheduled Bleeding on HRT:
USOC Referral Gynaecology Sci-gateway > RIE > Gynaecology > LI Basic sign referral (select priority USOC) and simultaneous referral to Radiology for PMB USS Sci-Gateway > ELCH/LB/RIE/SJH > Clinical Radiology > LI PMB (No HRT)
6.For patients with ongoing bleeding at 6 weeks since stopping HRT Unscheduled Bleeding on HRT link:
USOC Referral Gynaecology Sci-gateway > RIE > Gynaecology > LI Basic sign referral (select priority USOC) and simultaneous referral to Radiology for PMB USS Sci-Gateway > ELCH/LB/RIE/SJH > Clinical Radiology > LI PMB (No HRT)












