Family History of Breast and or Ovarian Cancer – RefHelp (nhslothian.scot)
Who to refer:
Women with ovarian pathology identified on USS (see flowchart)
Who not to refer:
This guideline relates to women in whom ovarian pathology has been identified on USS. It does not relate to women presenting with acute symptoms in which a diagnosis of an ovarian cyst accident is suspected. In such cases, patients should be discussed with the on-call gynaecology doctor via switchboard.
How to refer:
Sci-Gateway > RIE or SJH > Gynaecology > Ovarian Pathology
The use of sequential or continuous HRT is not thought to affect Ca125, which when indicated, can be checked at any time.
RCOG Green-top Guideline No. 34 Ovarian Cysts in Postmenopausal Women https://www.rcog.org.uk/en/guidelines-research-services/guidelines/gtg34/
Simple Adnexal Cysts: SRU Consensus Conference Update on Follow up and Reporting. Radiology 2019; 293:359-371.
Risk of Malignant Ovarian Cancer based upon ultrasonography findings in a large, unselected population. JAMA Internal Medicine 2019; 179:71-78. Smith-Bindman et al.
Risk of complications in patients with conservatively managed ovarian tumours (IOTA5): a 2-year interim analysis of a multicentre, prospective, cohort study. Lancet Oncol 2019 20:448-458. Froyman et al.
Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial. Lancet 2021; 397:2182-2193 Menon et al.
