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Barrett’s Oesophagus

Requires Surveillance:

If patient has <1cm of Barrett’s oesophagus then no biopsies and no follow up required.​

For those with histologically proven Barrett’s oesophagus ≥1cm length, follow up interval depends on presence of dysplasia and length of Barrett’s segment*

* Follow-up by oesophageal cell collection device ( “Cytosponge”),  with endoscopy for selected cases.

J.B & I.P 28-08-24

Do not routinely offer OGD to those with GORD to diagnose Barrett’s especially if age <55

Consider referral if long standing GORD especially if

  • family history of Barrett’s or oesophageal adenocarcinoma
  • Age 55 years or older
  • long duration of symptoms
  • worsening symptoms
  • male
  • previous hiatus hernia or oesophagitis
  • obesity (BMI>30)
  • smoker

Barrett’s oesophagus Treatment

  • Offer long term maintenance full dose PPI (eg omeprazole 20mg daily)
  • Remain on full dose PPI (high dose may be necessary to control symptoms)
    • High dose PPI (eg omeprazole 40mg daily)
  • Switch to another PPI at full or high dose if initial PPI fails to control symptoms

Follow up of Barrett’s oesophagus (NHS Lothian)**

  • If patient has < 1cm of Barrett’s oesophagus, then no biopsies and no follow up required
  • After diagnosis follow up interval depends on:
    • presence of dysplasia and length of Barrett’s segment
  • If dysplasia is absent at index OGD, next follow-up should be by Cytosponge, repeated in 1 year
  • If dysplasia is absent at 1year, subsequent follow up interval depends on length of Barrett’s segment.

Barrett’s >3cm

All others

**Follow-up currently by Cytosponge, with endoscopy for selected cases

Further Information

The presence of low- or high-grade dysplasia will usually lead to MDT referral and/or endoscopic therapy: this will be sorted in secondary care once histology results available

If there is doubt about presence of dysplasia OGD is repeated after 6 months (usually with increased PPI dose)