Image: MERS-CoV by National Institute of Allergy and Infectious Diseases – NIAID

Current Projects

We have a broad and exciting portfolio of diverse research projects from essential basic science to cutting edge clinical trials

OUR PROJECTS

CAB LA PrEP Cohort Study

Prospective Cohort Study to Assess Cabotegravir for PrEP in Europe
Anchor

A Phase 3 Randomized, Double-Blind, Placebo-Controlled,
Multicenter Study to Evaluate the Safety and Efficacy of
CD388, a Novel Long-Acting Antiviral Conjugate, for the
Prevention of Influenza in Adults and Adolescents at Higher
Risk of Developing Influenza Complications
Fortress

A European, multicentre, non-comparative, noninterventional,prospective clinical registry to evaluate the clinical outcome and safety of the treatment of severely infected patients with fosfomycin i.v.
Positive Voices

Positive Voices: National Survey of People with HIV
MR907-2502: CPA Rezafungin

A phase 2, multicentre, open-label, single arm study to evaluate the effectiveness and safety of rezafungin (as acetate) in the treatment of chronic pulmonary aspergillosis (CPA) in patients with limited treatment options
id.DRIVE

Surveillance study of respiratory pathogens in adults hospitalised for SARI across Europe
Coral

A non-interventional, mixed-methods, prospective cohort study to
characterise the real-world implementation, roll out, safety and patient experience of the
long-acting injectable HIV treatment regimen of 2-monthly cabotegravir and rilpivirine
GeoSentinel

GeoSentinel, the Global Surveillance Network of the International Society of Travel Medicine (ISTM)
Restorative 303

A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of VE303 for Prevention of Recurrent Clostridioides difficile Infection
STRIVE

An open-label dose-escalating study evaluating the safety, pharmacokinetics and antiviral activity of IMC-M113V in HLA-A*02:01 positive, virologically suppressed subjects with chronic HIV infection
Nova 301

A Phase 3, Randomized, Observer-blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of mRNA-1403, a Multivalent Candidate Vaccine to Prevent Norovirus Acute Gastroenteritis in Adults ≥18 Years of Age
SNAP

Staphylococcus aureus Network Adaptive Platform trial
UKAR

UK Antimicrobial Registry
CASCADE

An investigation into the medical and lived experiences of people with recently acquired HIV in Europe and Canada
RECOVERY

Randomised Evaluation of COVID-19 Therapy
RIO

A randomised placebo controlled trial of ART plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) vs ART plus placebo in treated Primary HIV Infection on viral control off ART
EuroSIDA

The EuroSIDA network 2005-2009. Clinical and virological outcome of patients with HIV in Europe
PrEPaRe

Pre-exposure Prophylaxis Use in People Newly Diagnosed with HIV
HEAL-COVID

HElping Alleviate the Longer-term consequences of COVID-19 (HEAL-COVID)