
Past Projects
Previous Studies CIRG participated as a site
PAST PROJECTS

AMR in Sewage
Using Sewage as a Surveillance Tool for Antimicrobial Resistance

AZD2816 (COV-Variant)
A Phase II/III Partially Double-Blinded, Partially Randomised, Multinational, Active-Controlled Study to Determine the Safety and Immunogenicity of AZD2816, a Vaccine for the Prevention of COVID-19 Caused by Variant Strains of SARS-CoV-2

COV009 Oxford Vaccine Study
Post-approval follow-up for the COV001 and 002 trials, to determine the long-term safety and character of immunological response to the ChAdOx1 nCoV-19 coronavirus vaccine

Intestinal Microbiota in C. diff
Role of the Intestinal Microbiota in Clostridium difficile infection and recurrence

COV002 Oxford Vaccine Study
A phase 2/3 study to determine the efficacy, safety and immunogenicity of the candidate Coronavirus Disease (COVID-19) vaccine ChAdOx1 nCoV-19

Discover
A Phase 3, Randomized, Double-blind Study to Evaluate the Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Exposure Prophylaxis in Men and Transgender Women Who Have Sex with Men and Are At Risk of HIV-1 Infection

Optimisation of HCV Therapy
Developing a GP-led Hepatitis C Treatment Pathway

WISARD
An Open-label, multi-centre, randomised, switch study to evaluate the virological efficacy over 96 weeks of 2-Drug therapy with DTG/RPV FDC in Antiretroviral treatmentexperienced HIV-1 infected subjects virologically suppressed with Nnrtis Resistance Mutation K103N

Clover
A Phase 3, Placebo-Controlled, Randomised, Observer-blinded Study to Evaluate the efficacy, safety, and tolerability of a clostridium difficile vaccine in adults 50 years of age and older

CHIPS+
CHIPS+: Optimising the Health of Young People with HIV in their Transition from Paediatric to Adult Care

ARK
Antibiotic Reduction and Conservation in Hospitals (ARK-Hospital)

TOPAZ-I (M14-423)
An Open-Label, Multicenter Study to Evaluate Long-Term Outcomes With ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 With or Without Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection (TOPAZ-I)

COV-COMPARE
A Randomised, Observer-Blind, Controlled, Superiority Study to Compare the Immunogenicity Against COVID-19, of VLA2001 Vaccine to AZD1222 Vaccine, in Adults

MIDAS
Measuring the impact of Improved Diagnostics on Antimicrobial Stewardship in Respiratory Tract Infection
OUR MEMBERS
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