OUR PROJECTS

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  Aspergillosis

  A phase 2, multicentre, open-label, single arm study to evaluate the effectiveness and safety of rezafungin (as acetate) in the treatment of chronic pulmonary aspergillosis (CPA) in patients with limited treatment options

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  id.DRIVE

  Surveillance study of respiratory pathogens in adults hospitalised for SARI across Europe

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  Coral

  A non-interventional, mixed-methods, prospective cohort study to
  characterise the real-world implementation, roll out, safety and patient experience of the
  long-acting injectable HIV treatment regimen of 2-monthly cabotegravir and rilpivirine

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  GeoSentinel

  GeoSentinel, the Global Surveillance Network of the International Society of Travel Medicine (ISTM)

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  Restorative 303

  A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study of VE303 for Prevention of Recurrent Clostridioides difficile Infection

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  STRIVE

  An open-label dose-escalating study evaluating the safety, pharmacokinetics and antiviral activity of IMC-M113V in HLA-A*02:01 positive, virologically suppressed subjects with chronic HIV infection

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  Fluent

  A Phase 3, Randomized, Observer-blind, Active-controlled Study to Investigate the Safety, Reactogenicity, and Efficacy of mRNA-1010 Candidate Seasonal Influenza Vaccine Compared with a Licensed Inactivated Seasonal Influenza Vaccine in Adults ≥50 Years of Age

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  Nova 301

  A Phase 3, Randomized, Observer-blinded, Placebo-Controlled Study to Evaluate the Safety and Efficacy of mRNA-1403, a Multivalent Candidate Vaccine to Prevent Norovirus Acute Gastroenteritis in Adults ≥18 Years of Age

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  SNAP

  Staphylococcus aureus Network Adaptive Platform trial

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  B-WELL 1

  Phase 3 Multicenter, Randomized, Double-Blind, Study to Assess the Efficacy and Safety of Treatment with Bepirovirsen in HBeAg_negative Nucleos(t)ide Analogue-treated Participants with Chronic Hepatitis B Virus

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  UKAR

  UK Antimicrobial Registry

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  MISTRAL

  Microbiome-based stratification of individuals at risk of HIV-1 acquisition, chronic clinical complications, antimicrobial drug resistance, and unresponsiveness to therapeutic HIV-1 vaccination

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  CASCADE

  An investigation into the medical and lived experiences of people with recently acquired HIV in Europe and Canada

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  RECOVERY

  Randomised Evaluation of COVID-19 Therapy

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  RIO

  A randomised placebo controlled trial of ART plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) vs ART plus placebo in treated Primary HIV Infection on viral control off ART

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  EuroSIDA

  The EuroSIDA network 2005-2009. Clinical and virological outcome of patients with HIV in Europe

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  PrEPaRe

  Pre-exposure Prophylaxis Use in People Newly Diagnosed with HIV

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  HEAL-COVID

  HElping Alleviate the Longer-term consequences of COVID-19 (HEAL-COVID)

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  ISARIC 4C

  ISARIC/WHO Clinical Characterisation Protocol for Severe Emerging Infections in the UK (CCP-UK) (Scotland)