Lower respiratory tract infections (LRTIs) can be caused by a broad array of pathogens, including various respiratory viruses such as influenza A and B, SARS-CoV-2, respiratory syncytial virus (RSV), adenovirus, or Parainfluenza viruses. Most often, infection with any of these pathogens causes mild illness, such as a cold, but in some cases can become very serious and require hospitalisation.

id.DRIVE is a non-interventional multi-country, multi-centre, hospital-based surveillance study of viral respiratory pathogens in adults hospitalised for SARI. The study is designed to monitor the burden of disease of multiple viral respiratory pathogens and to study preparedness for future impact and effectiveness studies.

Primary objectives
– To calculate the proportion of laboratory samples positive for each viral respiratory pathogen of interest, among adult patients hospitalised with SARI.
– To characterise adult SARI patients (including age, gender, protective- and risk factors, specific treatments, and healthcare utilisation outcomes), overall and by viral respiratory pathogen of interest.

Secondary objectives
– To investigate the prevalence of co-infection with the viral respiratory pathogens of interest1, in adult patients hospitalised with SARI, and the impact on healthcare utilisation outcomes.

Exploratory objectives
– To calculate pathogen-specific SARI incidences and describe trends in hospitalised adults (time period, country, level of severity) .
– To perform feasibility assessments for future respiratory disease studies within the id.DRIVE Study Network (e.g., effectiveness studies, impact studies).

MAIN FUNDING BODY