Dr Simon Dewar
Consultant in Medical Microbiology
Position:
Consultant in Medical Microbiology, Clinical Lead Antimicrobial Management Team, Honorary Lecturer University of Edinburgh
Email:
simon.dewar@nhslothian.scot.nhs.uk
Research Interests:
Antimicrobial Stewardship
Drug Discovery
Infection Prevention and Control
Projects/Grants:
Lothian PI for TIDE: Trial of De-colonisation
A multi-centre, randomised controlled, non-inferiority and cost effectiveness trial comparing Polyhexanide and Chlorhexidine with Neomycin to Mupirocin for nasal methicillin resistant Staphylococcus aureus (MRSA) decolonisation amongst adult hospital in-patients.
Background:
Dr Dewar did his undergraduate medical studies at the University of Dundee, also attaining a first class BMSc in Neurosciences. He completed his specialist training in medical microbiology in the North East of England and during this time undertook a PhD, University of Dundee, focusing on the folate pathway and drug discovery in African trypanosomiasis. He has worked as a microbiology consultant in NHS Lothian since 2019 and is currently the clinical lead for Lothian’s antimicrobial management team. His particular interests are antimicrobial stewardship, drug discovery and infection prevention and control.
Key Publications
2024
Arshad, A., Russell, C. D., Moore, B., & Dewar, S. (2024). The ‘Other’ in AWaRe. JAC-antimicrobial resistance, 6(6), dlae196.
2019
Dewar S, Vass D, Mackenzie F, Parcell BJ (2019) Point-of-care testing by healthcare workers for detection of meticillin-resistant Staphylococcus aureus, Clostridioides difficile, and norovirus. Journal of Hospital Infection 103, 444-53
2016
Dewar S, Sienkiewicz N, Ong HB, Wall RJ, Horn D, Fairlamb AH (2016). The Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei. Journal of Biological Chemistry 291, 24768-24778.
2014
Dewar S, Reed LC, Koerner RJ (2014). Emerging clinical role of pivmecillinam in the treatment of urinary tract infection in the context of multidrug-resistant bacteria. Journal of Antimicrobial Chemotherapy 69, 303-308.
All Publications
2024
Russell, C. D., Berry, K., Cooper, G., Sim, W., Lee, R. S., Gan, T. Y., Donlon, W., Besu, A., Heppenstall, E., Tysall, L., Robb, A., Dewar, S., Smith, A., & Fowler, V. G., Jr (2024). Distinct Clinical Endpoints of Staphylococcus aureus Bacteraemia Complicate Assessment of Outcome. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 79(3), 604–611.
Arshad, A., Russell, C. D., Moore, B., & Dewar, S. (2024). The ‘Other’ in AWaRe. JAC-antimicrobial resistance, 6(6), dlae196.
Maaike C Swets, Zsuzsa Bakk, Annette C Westgeest, Karla Berry, George Cooper, Wynne Sim, Rui Shian Lee, Tze Yi Gan, William Donlon, Antonia Besu, Emily Heppenstall, Luke Tysall, Simon Dewar, Mark de Boer, Vance G Fowler, David H Dockrell, Guy E Thwaites, Miquel Pujol, Natàlia Pallarès, Cristian Tebé, Jordi Carratalà, Alexander Szubert, Geert H Groeneveld, Clark D Russell, Clinical Subphenotypes of Staphylococcus aureus Bacteremia, Clinical Infectious Diseases, Volume 79, Issue 5, 15 November 2024, Pages 1153–1161,
2022
Kelly J, Tysall L, Dewar S (2022) Daptomycin susceptibility testing and therapeutic use in enterococcal bloodstream infection (EBSI) in a setting with high rates of vancomycin-resistant Enterococcus faecium (VREfm) Journal of Antimicrobial Chemotherapy 77 1432-1435
2021
Ahmed W, Dewar S, Williams R, Stansby G, Harris K, Weiand D (2021) Lawsonella clevelandensis is a Rare Cause of Infected Chronic Contained Rupture of Abdominal Aortic Aneurysm. Access Microbiology 3, 000183
2019
Dewar S, Vass D, Mackenzie F, Parcell BJ (2019) Point-of-care testing by healthcare workers for detection of meticillin-resistant Staphylococcus aureus, Clostridioides difficile, and norovirus. Journal of Hospital Infection 103, 444-53.
2016
Dewar S, Sienkiewicz N, Ong HB, Wall RJ, Horn D, Fairlamb AH (2016). The Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei. Journal of Biological Chemistry 291, 24768-24778.
Gibson MW, Dewar S, Ong HB, Sienkiewicz N, Fairlamb AH (2016). Trypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate Synthase. PLoS Neglected Tropical Diseases 10, e0004714.
2015
Dewar S, Weir-McCall JR, Batchelor L, Cole S, Parcell BJ (2015). Bacillus Anthracis Meningitis During an Outbreak of Injectional Anthrax, Scotland, UK. Clinical Microbiology and Infection 21, e49-50.
2014
Dewar S, Reed LC, Koerner RJ (2014). Emerging clinical role of pivmecillinam in the treatment of urinary tract infection in the context of multidrug-resistant bacteria. Journal of Antimicrobial Chemotherapy 69, 303-308.
2013
Dewar S, Bignardi GE, Settle C (2013). Increase in reported Clostridium difficile cases as unintended consequence of enhanced norovirus testing. Journal of Hospital Infection 85, 240-241.
2012
Macaskill EJ, Dewar S, Purdie CA, Brauer K, Baker L, and Brown DC (2012). Sentinel node biopsy in breast cancer has a greater node positivity rate than axillary node sample: results from a retrospective analysis. European Journal of Surgical Oncology 38, 662-669.
