{"id":25623,"date":"2025-10-28T18:30:57","date_gmt":"2025-10-28T18:30:57","guid":{"rendered":"https:\/\/apps.nhslothian.scot\/refhelp\/?page_id=25623"},"modified":"2025-10-29T09:39:25","modified_gmt":"2025-10-29T09:39:25","slug":"microbiology","status":"publish","type":"page","link":"https:\/\/apps.nhslothian.scot\/refhelp\/microbiology\/","title":{"rendered":"Microbiology"},"content":{"rendered":"\n<p>Microbiology is concerned with the detection, isolation and identification of microbes in clinical samples.<\/p>\n\n\n\n<p>Further information on our service can be found at: <a href=\"https:\/\/edinburghlabmed.co.uk\/Specialities\/CellScience\/Microbiology\/Pages\/default\" target=\"_blank\" rel=\"noreferrer noopener\">Microbiology | Edinburgh and Lothians Laboratory Medicine<\/a>.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><u>To contact the laboratory<\/u><\/strong><strong><u><\/u><\/strong><\/h2>\n\n\n\n<p>To discuss with the microbiology <strong>laboratory team<\/strong>, including results,<\/p>\n\n\n\n<p>Mon-Fri 09:00-17:00 Sat-Sun 09:00-16:00:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>RIE laboratory &#8211; for all sites except SJH in hours &#8211; 0131 242 6021 (26021)<\/li>\n\n\n\n<li>SJH laboratory \u2013 01506 523080 (53080).<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><u>To contact for clinical advice<\/u><\/strong><\/h2>\n\n\n\n<p>For <strong>clinical microbiology advice<\/strong>, please use the GP advice email:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"mailto:loth.gpmicroadvice@nhs.scot\" target=\"_blank\" rel=\"noreferrer noopener\">loth.gpmicroadvice@nhs.scot<\/a><\/li>\n\n\n\n<li>This is&nbsp;monitored Monday &#8211; Friday, 9am &#8211; 5pm.&nbsp;If an email is received before 3pm on a normal working day we will aim to respond by 5pm that day.<\/li>\n\n\n\n<li><strong><em>Emails are NOT monitored during weekends or public holidays.<\/em><\/strong><\/li>\n<\/ul>\n\n\n\n<p><strong>URGENT clinical microbiology advice<\/strong> is available via telephone:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>0131 536 3373 (63373) and choose option 4 for medical microbiology.<\/li>\n\n\n\n<li>During out-of-hours\/weekends\/public holidays&nbsp;URGENT medical microbiology advice is available via NHSL switchboard 0131 536 1000.&nbsp;<\/li>\n<\/ul>\n\n\n\n<p>Note for virological queries there is an email inbox: &nbsp;<a href=\"mailto:virologyadvice@nhs.scot\" target=\"_blank\" rel=\"noreferrer noopener\">loth.virologyadvice@nhs.scot<\/a>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><u>Guidance is available for<\/u><\/strong>:<\/h2>\n\n\n\n<p><strong>Infection Prevention Control<\/strong> advice &#8211; <a href=\"http:\/\/intranet.lothian.scot.nhs.uk\/Directory\/InfectionPreventionAndControl\/Pages\/default.aspx\" target=\"_blank\" rel=\"noreferrer noopener\">Infection Prevention and Control<\/a><\/p>\n\n\n\n<p><strong>Virology<\/strong> contact information and advice &#8211; <a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/laboratoryservices\/virology\/\" target=\"_blank\" rel=\"noreferrer noopener\">Virology \u2013 RefHelp<\/a>.<\/p>\n\n\n\n<p><strong>Specific guidance<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/formulary.nhs.scot\/east\/infections\/\" target=\"_blank\" rel=\"noreferrer noopener\">Antimicrobial prescribing advice &#8211; community<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/rightdecisions.scot.nhs.uk\/antimicrobial-prescribing-nhs-lothian\/\" target=\"_blank\" rel=\"noreferrer noopener\">Antimicrobial guidance \u2013 more detailed \/ specialist \/ acute<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/edinburghlabmed.co.uk\/TestDirectory\/Pages\/default\" target=\"_blank\" rel=\"noreferrer noopener\">Diagnostic tests<\/a> including how to request, turnaround time, specimen requirements<\/li>\n\n\n\n<li><a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/infectiousdiseases\/\" target=\"_blank\" rel=\"noreferrer noopener\">Infectious Diseases<\/a> including <a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/infectiousdiseases\/opat\/\" target=\"_blank\" rel=\"noreferrer noopener\">OPAT<\/a> referrals.<\/li>\n<\/ul>\n\n\n\n<p>Please see useful guidelines about common infections under the speciality sections:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/otitisexterna\/\" target=\"_blank\" rel=\"noreferrer noopener\">Otitis Externa \u2013 RefHelp (nhslothian.scot)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/vaginaldischarge-vulvitis\/\" target=\"_blank\" rel=\"noreferrer noopener\">Vaginal Discharge \u2013 RefHelp (nhslothian.scot)<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/eur01.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fapps.nhslothian.scot%2Frefhelp%2Fguidelines%2Frecurrentutisfemale%2F&amp;data=05%7C01%7CEwan.Olson%40nhslothian.scot.nhs.uk%7C955835e994f24340dfda08db24a54f69%7C10efe0bda0304bca809cb5e6745e499a%7C0%7C0%7C638144064642357020%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C3000%7C%7C%7C&amp;sdata=3alYiTZzc8vQcBBIZm8TIOmrszVBxNKhaF2JUendb%2Fo%3D&amp;reserved=0\" target=\"_blank\" rel=\"noreferrer noopener\">Recurrent UTIs \u2013 RefHelp (nhslothian.scot)<\/a><\/li>\n<\/ul>\n\n\n\n<p><strong>NICE CKS<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Contains advice on many common infections in primary care and can cover unusual presentations e.g. threadworms in pregnancy.<\/li>\n\n\n\n<li><a href=\"https:\/\/cks.nice.org.uk\/specialities\/infections-infestations\/\" target=\"_blank\" rel=\"noreferrer noopener\">Infections and infestations | Specialities | CKS | NICE<\/a>.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\"><strong><u>FAQs<\/u><\/strong>:<\/h2>\n\n\n\n<p><strong>1.How should chronic ulcers\/wounds be assessed for signs of infection?<\/strong><\/p>\n\n\n\n<p>a.The ERF has a series of resources, including the Ropper ladder, on managing suspected infection in chronic wounds here: <a href=\"https:\/\/eur01.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fformulary.nhs.scot%2Feast%2Fwound-care%2Fwound-management%2Fantimicrobial-wound-management-products%2F&amp;data=05%7C02%7CCallum.Mutch%40nhs.scot%7C5a2e4b440dc647c7ec6508ddd04b4419%7C10efe0bda0304bca809cb5e6745e499a%7C0%7C0%7C638895743857018791%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=cha%2FToOhkybIxWlqaHhWg1ZG7xjdHTT4JzvqbZbmRn0%3D&amp;reserved=0\" target=\"_blank\" rel=\"noreferrer noopener\">East Region Formulary &#8211; Wound Management<\/a><\/p>\n\n\n\n<p><strong>2. Mixed growth urines in symptomatic patients<\/strong><\/p>\n\n\n\n<p>a.<span style=\"letter-spacing: -0.1px\">If the patient has symptoms consistent with a UTI, treat empirically as per formulary guidance<\/span><\/p>\n\n\n\n<p>b.<span style=\"letter-spacing: -0.1px\">&#8220;Mixed growth&#8221; usually indicates contamination with vaginal, skin or bowel organisms. Suggest repeat sample if clinically indicated e.g. in pregnancy. Samples in boric acid containers (red top) are preferred to reduce overgrowth of contaminants before the samples arrive in the laboratory.<\/span><\/p>\n\n\n\n<p>c.If the patient does not have symptoms or signs of a UTI then treatment is not recommended, regardless of the amount of growth, unless the patient is a pregnant woman.<\/p>\n\n\n\n<p><strong>3.Can I use oral flucloxacillin for a mixture of flucloxacillin sensitive Staph aureus and Beta haemolytic streps in a swab?<\/strong><\/p>\n\n\n\n<p>a.<span style=\"letter-spacing: -0.1px\">Oral flucloxacillin alone is expected to be effective for mild infections caused by Streptococcus pyogenes (Group A Streptococcus) and Streptococcus dysgalactiae (Groups C and G Streptococcus).<\/span><\/p>\n\n\n\n<p>b.However, Streptococcus agalactiae (Group B Strep) often is less susceptible to flucloxacillin. Amoxicillin would be a better choice for Streptococcus agalactiae. Amoxicillin can be added to flucloxacillin in cases of mixed infections of Streptococcus agalactiae and Staphylococcus aureus.<\/p>\n\n\n\n<p><strong>4.How should I manage a patient with H. pylori whose symptoms have not responded to first- and second-line therapy, or in whom there are contraindications to usual care?<\/strong><\/p>\n\n\n\n<p>a.<span style=\"letter-spacing: -0.1px\">Gastroenterology leads on providing advice for Helicobacter infection. <\/span><\/p>\n\n\n\n<p>b.<span style=\"letter-spacing: -0.1px\">Please see <\/span><a style=\"letter-spacing: -0.1px\" href=\"https:\/\/eur01.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fapps.nhslothian.scot%2Frefhelp%2Fguidelines%2Fgastrointestinal%2Fhelicobacter-pylori%2F&amp;data=05%7C02%7CCallum.Mutch%40nhs.scot%7C5a2e4b440dc647c7ec6508ddd04b4419%7C10efe0bda0304bca809cb5e6745e499a%7C0%7C0%7C638895743857003614%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=Iblxn5nGfqCy8WXLhtxbxQHGgdPJ9BbO3mtS%2Fi9UKwg%3D&amp;reserved=0\" target=\"_blank\" rel=\"noreferrer noopener\">Helicobacter Pylori \u2013 RefHelp<\/a><\/p>\n\n\n\n<p>c.The formulary has prescribing information here: <a href=\"https:\/\/eur01.safelinks.protection.outlook.com\/?url=https%3A%2F%2Fformulary.nhs.scot%2Feast%2Fgastro-intestinal-system%2Fgastro-oesophageal-disorders%2Fdyspepsia%2F%3Fm%3Dh-pylori-associated-dyspepsia&amp;data=05%7C02%7CCallum.Mutch%40nhs.scot%7C5a2e4b440dc647c7ec6508ddd04b4419%7C10efe0bda0304bca809cb5e6745e499a%7C0%7C0%7C638895743856977381%7CUnknown%7CTWFpbGZsb3d8eyJFbXB0eU1hcGkiOnRydWUsIlYiOiIwLjAuMDAwMCIsIlAiOiJXaW4zMiIsIkFOIjoiTWFpbCIsIldUIjoyfQ%3D%3D%7C0%7C%7C%7C&amp;sdata=CboeBGgAoMeqQhqeIrG5f%2Bk5ZdIxMFYBA7RMj48h%2FgE%3D&amp;reserved=0\" target=\"_blank\" rel=\"noreferrer noopener\">East Region Formulary &#8211; H. pylori<\/a><\/p>\n\n\n\n<p><em>If your H Pylori query is not answered by the above, then please contact Gastroenterology by email for advice.<\/em><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Microbiology is concerned with the detection, isolation and identification of microbes in clinical samples. Further information on our service can be found at: Microbiology | Edinburgh and Lothians Laboratory Medicine.&nbsp; To contact the laboratory To discuss with the microbiology laboratory team, including results, Mon-Fri 09:00-17:00 Sat-Sun 09:00-16:00: To contact for clinical advice For clinical microbiology<\/p>\n","protected":false},"author":7,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"categories":[288],"class_list":["post-25623","page","type-page","status-publish","hentry","category-laboratoryservices"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"aparnaamanna","author_link":"https:\/\/apps.nhslothian.scot\/refhelp\/author\/aparnaamanna\/"},"rttpg_comment":0,"rttpg_category":" <a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/category\/laboratoryservices\/\" rel=\"tag\">Laboratory Services<\/a>","rttpg_excerpt":"Microbiology is concerned with the detection, isolation and identification of microbes in clinical samples. Further information on our service can be found at: Microbiology | Edinburgh and Lothians Laboratory Medicine.&nbsp; To contact the laboratory To discuss with the microbiology laboratory team, including results, Mon-Fri 09:00-17:00 Sat-Sun 09:00-16:00: To contact for clinical advice For clinical microbiology","_links":{"self":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages\/25623","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/comments?post=25623"}],"version-history":[{"count":3,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages\/25623\/revisions"}],"predecessor-version":[{"id":25626,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages\/25623\/revisions\/25626"}],"wp:attachment":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/media?parent=25623"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/categories?post=25623"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}