{"id":24683,"date":"2025-07-17T12:21:20","date_gmt":"2025-07-17T11:21:20","guid":{"rendered":"https:\/\/apps.nhslothian.scot\/refhelp\/?page_id=24683"},"modified":"2025-07-24T12:21:59","modified_gmt":"2025-07-24T11:21:59","slug":"burning-legs","status":"publish","type":"page","link":"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/neurology\/burning-legs\/","title":{"rendered":"Burning Legs"},"content":{"rendered":"\n<p><a href=\"https:\/\/apps.nhslothian.scot\/files\/sites\/2\/Burning-legs-2025-final.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Burning-legs-2025-final.pdf<\/a><\/p>\n\n\n\n<p><strong>Information<\/strong><\/p>\n\n\n\n<p>Sensory symptoms are one of the commonest issues for which we provide advice to primary care. This advice sheet is to support GPs and patients when faced with burning and tingling in the feet\/extremities, to supplement existing advice about idiopathic axonal neuropathy, restless legs syndrome, and benign sensory symptoms.<\/p>\n\n\n\n<p><strong>Sensory disturbance does not mean \u2018peripheral neuropathy\u2019<\/strong>       <\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignright size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"301\" height=\"330\" src=\"https:\/\/apps.nhslothian.scot\/files\/sites\/2\/Burning-Legs.png\" alt=\"Burning Legs\" class=\"wp-image-24707\" style=\"width:163px;height:auto\" srcset=\"https:\/\/apps.nhslothian.scot\/files\/sites\/2\/Burning-Legs.png 301w, https:\/\/apps.nhslothian.scot\/files\/sites\/2\/Burning-Legs-274x300.png 274w\" sizes=\"auto, (max-width: 301px) 100vw, 301px\" \/><figcaption><span class=\"media-credit\">NHS Lothian<\/span><\/figcaption><\/figure>\n<\/div>\n\n\n<p>Disturbed sensation of extremities (e.g. tingling, numbness, crawling, pain, burning, etc), most commonly of the feet but sometimes spreading more proximally and\/or involving the hands, is a common reason for referral to neurology. It is often more noticeable at night, disturbing sleep.&nbsp;<\/p>\n\n\n\n<p>These symptoms are often referred to by non-neurologists as \u201cperipheral neuropathy\u201d, but this is a specific diagnosis and only accounts for some of the people affected. We encourage doctors not to use the term \u201cPeripheral neuropathy\u201d unless confirmed as the cause.&nbsp; Peripheral neuropathy is almost never the likely cause when symptoms are intermittent.<\/p>\n\n\n\n<p><strong>\u2018Idiopathic\u2019 is the commonest cause<\/strong><\/p>\n\n\n\n<p>In our experience, \u201cno identifiable cause (idiopathic)\u201d is the most common cause. Sensory symptoms, especially burning\/pain, are commonly worse at night or on walking. Causes, in order of frequency, include:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Idiopathic<\/strong><\/li>\n\n\n\n<li><strong>Peripheral neuropathy <\/strong>(most commonly idiopathic axonal neuropathy in over 65s)<\/li>\n\n\n\n<li><strong>Lumbar spinal stenosis and radiculopathy<\/strong><\/li>\n\n\n\n<li><strong>Restless Legs Syndrome (RLS).<\/strong> Burning sensation may complicate RLS, so asking about motor restlessness is sensible. Some cases may also involve involuntary movement of toes \u2013 \u201cPainful legs and moving toes syndrome\u201d.<\/li>\n\n\n\n<li><strong>Small fibre neuropathy<\/strong> (including related to diabetes or alcohol). This doesn\u2019t show on nerve conduction studies, and skin biopsy to look at nerve fibre density is not a reliable way to make the diagnosis. It\u2019s therefore a clinical diagnosis, and the management is symptomatic.<\/li>\n\n\n\n<li><strong>Ill-fitting footwear, skin problems (eg tinea)<\/strong><\/li>\n\n\n\n<li><strong>Complex regional pain syndrome <\/strong>is a chronic nociplastic pain syndrome which can involve burning and redness, typically after injury.&nbsp; <strong>Erythromelalgia<\/strong> is a poorly understood condition that causes redness of the feet. It can overlap with complex regional pain syndrome.<\/li>\n<\/ul>\n\n\n\n<p><strong>Diagnosis and examination<\/strong><\/p>\n\n\n\n<p>Diagnosis is clinical. Examination is rarely helpful, but look for positive evidence of a neuropathy, e.g. loss of ankle jerks, and distal motor weakness.<\/p>\n\n\n\n<p><strong>Do they need investigation in primary care?<\/strong><\/p>\n\n\n\n<p>A peripheral neuropathy blood screen is sensible (see <a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/neurology\/mild-axonal-peripheral-neuropathy\/\" target=\"_blank\" rel=\"noreferrer noopener\">Axonal neuropathy <\/a>advice page on Refhelp), adding a ferritin if concerns about restless legs syndrome (see <a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/guidelines\/neurology\/restless-legs-syndrome-rls\/\" target=\"_blank\" rel=\"noreferrer noopener\">RLS <\/a>advice page on Refhelp).<\/p>\n\n\n\n<p><strong>Do they need to see a Neurologist?<\/strong><\/p>\n\n\n\n<p>Not usually, but we are happy to discuss is you have concerns.<\/p>\n\n\n\n<p>If symptoms are confined to the toes\/feet, we will usually provide advice rather than arrange an appointment.<\/p>\n\n\n\n<p><strong>General Lifestyle Advice<\/strong><\/p>\n\n\n\n<p>As the symptoms often trouble people mostly at night, careful attention to sleep hygiene is important, restricting alcohol\/caffeine intake, managing stress, optimising the bedroom environment, etc.<\/p>\n\n\n\n<p><strong>Medical treatment<\/strong><\/p>\n\n\n\n<p>Neuropathic pain drugs only help neuropathic pain (and even then, only sometimes). There are no drugs that help numbness or tingling, although we commonly find that drugs are mistakenly prescribed for these symptoms.<\/p>\n\n\n\n<p>If there is pain strongly suggesting a neuropathic cause, then consider the usual options (gabapentin, pregabalin, duloxetine, tricyclics, etc), but success is often limited, and withdraw unless there is persisting, unequivocal benefit.<\/p>\n\n\n\n<div class=\"wp-block-getwid-tabs\" data-active-tab=\"0\"><ul class=\"wp-block-getwid-tabs__nav-links\"><\/ul>\n<div class=\"wp-block-getwid-tabs__nav-link\"><span class=\"wp-block-getwid-tabs__title-wrapper\"><a href=\"#\"><span class=\"wp-block-getwid-tabs__title\">Referral Guidelines<\/span><\/a><\/span><\/div><div class=\"wp-block-getwid-tabs__tab-content-wrapper\"><div class=\"wp-block-getwid-tabs__tab-content\">\n<p><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-getwid-tabs__nav-link\"><span class=\"wp-block-getwid-tabs__title-wrapper\"><a href=\"#\"><span class=\"wp-block-getwid-tabs__title\">Primary Care Management<\/span><\/a><\/span><\/div><div class=\"wp-block-getwid-tabs__tab-content-wrapper\"><div class=\"wp-block-getwid-tabs__tab-content\">\n<p><\/p>\n<\/div><\/div>\n\n\n\n<div class=\"wp-block-getwid-tabs__nav-link\"><span class=\"wp-block-getwid-tabs__title-wrapper\"><a href=\"#\"><span class=\"wp-block-getwid-tabs__title\">Resources and Links<\/span><\/a><\/span><\/div><div class=\"wp-block-getwid-tabs__tab-content-wrapper\"><div class=\"wp-block-getwid-tabs__tab-content\">\n<p><\/p>\n<\/div><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Burning-legs-2025-final.pdf Information Sensory symptoms are one of the commonest issues for which we provide advice to primary care. This advice sheet is to support GPs and patients when faced with burning and tingling in the feet\/extremities, to supplement existing advice about idiopathic axonal neuropathy, restless legs syndrome, and benign sensory symptoms. Sensory disturbance does not<\/p>\n","protected":false},"author":6,"featured_media":0,"parent":4173,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"categories":[1274],"class_list":["post-24683","page","type-page","status-publish","hentry","category-https-apps-nhslothian-scot-refhelp-burning-legs"],"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"rttpg_featured_image_url":null,"rttpg_author":{"display_name":"heatherlevy","author_link":"https:\/\/apps.nhslothian.scot\/refhelp\/author\/heatherlevy\/"},"rttpg_comment":0,"rttpg_category":" <a href=\"https:\/\/apps.nhslothian.scot\/refhelp\/category\/neurology\/https-apps-nhslothian-scot-refhelp-burning-legs\/\" rel=\"tag\">Burning Legs<\/a>","rttpg_excerpt":"Burning-legs-2025-final.pdf Information Sensory symptoms are one of the commonest issues for which we provide advice to primary care. This advice sheet is to support GPs and patients when faced with burning and tingling in the feet\/extremities, to supplement existing advice about idiopathic axonal neuropathy, restless legs syndrome, and benign sensory symptoms. Sensory disturbance does not","_links":{"self":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages\/24683","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/comments?post=24683"}],"version-history":[{"count":5,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages\/24683\/revisions"}],"predecessor-version":[{"id":24866,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages\/24683\/revisions\/24866"}],"up":[{"embeddable":true,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/pages\/4173"}],"wp:attachment":[{"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/media?parent=24683"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/apps.nhslothian.scot\/refhelp\/wp-json\/wp\/v2\/categories?post=24683"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}